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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e73adb2e9ac62b70af3252652237511105677e8cc9507ad0e0ff2b2ee19d356f' 
  AND token = 'v+gmjhySY+Eh/ezGs4mmxnwjTTwzbkbRvay5G2tfiqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}