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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5856ffe9a24f4cc7f5e8cd175f98807a04a272d234f99a1aa12dfefe70f26503' 
  AND token = 'CxjqzIowwOzEDHl0F0R5icnzKeDVieEAIMgQBjdpees=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}