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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5ab0902d2667cdf6019bc237af0989c01cabf67a98f79500c52b009b5d32b3' 
  AND token = 'YUeMa5KxC3UNpeS5hg+vVP7F7Ho4gNv1FWOPaW68eZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}