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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c658428b0fb823e0ba6fdb8afff309548d815c93f525e5b349a23a45133b48' 
  AND token = 'r08F5dfSlm451CIng9+ZsBwdCfmipbLVmq3q34lq8C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}